ADAM-MC2 | Automated fluorescence cell counter

Key Features

• Measurements completed in <25s
• LED optics
• Ideal for cell therapy quality control
• Compatible with peripheral blood mononuclear cells (PBMCs), adipose stem cells, total white blood cells, primary cells, SVF-derived cells, CAR-T cells, and CAR-NK cells.
• Automated image analysis using CMOS detection technologies.
• Precise stage movements and sensitive CMOS detection for highly accurate results

Product Description

The ADAM-MC2 is a new standard in automated fluorescence cell counting. The instrument utilises sensitive fluorescence dye staining, LED optics, and CMOS detection technologies to make the cell analysis more accurate and reliable. It measures the number of total cells, viable cells, non-viable cells and shows viability results. Combined with a disposable microfluidic  chip, the operation is now extremely simple, easy, and cost-effective.

There are two methods of viability  measurement available with the ADAM-MC2. After the samples are stained with fluorescent dye, propidium iodide (PI) or acridine orange (AO), which intercalates  DNA to stain the nucleus  of target cells, ADAM-MC2 takes  fluorescent images automatically. The obtained images are processed by image analysis software integrated inside the system.

ADAM-MC2  provides  accurate  and  reliable  results  because  it counts aggregated and irregular-shaped cells.
-  Accurate count based on cell size and shape
-  Count aggregated cells individually
-  Debris is excluded from results

ADAM-MC2 can be used as a device for monitoring and QC of the cell numbers and viability in the process of manufacturing cells (CAR-T cells, stem cells, etc.) for Cell Therapy.
In addition, it is possible to use ADAM-MC2 depending on the cell types (Whole blood cell, PBMCs, etc.) that needs to be monitored during the manufacturing of cell therapy products.

More Information

Please click here to download a brochure describing the ADAM-MC2 automated fluorescence cell counter or here to view a video.

Ordering Information

Catalog Number	Product Name
ADAM-MC2	ADAM-MC2 fluorescence cell counter
AD4K-200*	AccuChip 4x kit (PI) | 4 channel:200 slides/kit: PI viability kit
AD4K-200AO	AccuChip 4x kit (AO/PI) | 4 channel:200 slides/kit: AO/PI viability kit
ADR-1000**	Accustain solution (PI Accustain solution)
ADR-1000AO	Accustain solution (AO/PI Accustain solution)
ADB-500	ADAM calibration bead

* AD4K-200: Total cells are counted by PI with lysis buffer.

** ADR-1000: Total cells are counted by PI with lysis buffer.

Specifications

Manufacturer	NanoEntek
Model number	ADAM-MC2
Cell line	Clumpy or single cell
Cell types	Peripheral blood mononuclear cells (PBMCs) | Adipose stem cells | Total white blood cells | Primary cells | SVF-derived cells (includes adipose-derived stem cells (ADSCs), preadipocytes, endothelial progenitor cells, immune cells (like T cells and macrophages), fibroblasts, and pericytes).
Compatible dyes	Propidium Iodide (PI) or Acridine Orange (AO)
Analysis time	<25s/test (4 channel)
Loading volume	13 µL/test (4 channel)
Measuring volume	3.4 µL/test (4 channel)
Measurement range	5 x 104 ~ 4 x 106 cells/mL (PI) 5 x 104 ~ 2 x 107 cells/mL (AO/PI)
Focus	Auto-focusing
Light source	4W green LED
Dimensions	277 mm x 276 mm x 270 mm
Weight	7 Kg
Connectivity	WIFI | USB dongle

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