ADAM-MC2 | Automated fluorescence cell counter (MC2)

Key Features

• Measurements completed in <25s
• LED optics
• Ideal for cell therapy quality control
• Compatible with peripheral blood mononuclear cells (PBMCs), adipose stem cells, total white blood cells, primary cells, SVF-derived cells, CAR-T cells, and CAR-NK cells
• Precise stage movements and sensitive CMOS detection technologies for automated image analysis and highly accurate results
• Utilises a disposable microfluidic chip

Product Description

The ADAM-MC2 represents a new standard in automated fluorescence cell counting. The instrument utilises sensitive fluorescence dye staining, LED optics, and CMOS detection technologies to make the cell analysis more accurate and reliable. The ADAM-MC2 measures the number of total cells, viable cells, non-viable cells and shows viability results. Accuracy is enhanced because the unit counts cells based on size and shape. Aggregated cells are counted individually and debris is excluded from results. The ADAM-MC2 utilises a disposable microfluidic chip to make the operation extremely simple, easy, and cost-effective.

There are two methods of viability measurement available with the ADAM-MC2. After the samples are stained with fluorescent dye, propidium iodide (PI) or acridine orange (AO), which intercalates DNA to stain the nucleus of target cells, ADAM-MC2 takes fluorescent images automatically. The obtained images are processed by image analysis software integrated inside the system.

ADAM-MC2 can be used as a device for monitoring and QC of cell numbers and viability in the process of manufacturing cells (CAR-T cells, stem cells, etc.) for Cell Therapy. This capability also allows other cell types such as whole blood cell, PBMCs, etc. to be monitored.

More Information

Please click here to download a brochure describing the ADAM-MC2 automated fluorescence cell counter or here to view a video.

Ordering Information

Catalog Number	Product Name
ADAM-MC2	ADAM-MC2 fluorescence cell counter
AD4K-200*	AccuChip 4x kit (PI) | 4 channel:200 slides/kit: PI viability kit
AD4K-200AO	AccuChip 4x kit (AO/PI) | 4 channel:200 slides/kit: AO/PI viability kit
ADR-1000**	Accustain solution (PI Accustain solution)
ADR-1000AO	Accustain solution (AO/PI Accustain solution)
ADB-500	ADAM calibration bead

* AD4K-200: Total cells are counted by PI with lysis buffer.

** ADR-1000: Total cells are counted by PI with lysis buffer.

Specifications

Manufacturer	NanoEntek
Model number	ADAM-MC2
Cell line	Clumpy or single cell
Cell types	Peripheral blood mononuclear cells (PBMCs) | Adipose stem cells | Total white blood cells | Primary cells | SVF-derived cells (includes adipose-derived stem cells (ADSCs), preadipocytes, endothelial progenitor cells, immune cells (like T cells and macrophages), fibroblasts, and pericytes).
Compatible dyes	Propidium Iodide (PI) or Acridine Orange (AO)
Analysis time	<25s/test (4 channel)
Loading volume	13 µL/test (4 channel)
Measuring volume	3.4 µL/test (4 channel)
Measurement range	5 x 104 ~ 4 x 106 cells/mL (PI) 5 x 104 ~ 2 x 107 cells/mL (AO/PI)
Focus	Auto-focusing
Light source	4W green LED
Dimensions	277 mm x 276 mm x 270 mm
Weight	7 Kg
Connectivity	WIFI | USB dongle

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