BS-010158-A03 | RTS-1 single position bioreactor for the non-invasive monitoring of cell growth in real-time with a temperature control range of 5°C above ambient to +70°C








Key Features

  • Patented Reverse-Spin® technology non-invasively optimises mixing and oxygenation for aerobic cell cultivation
  • Near-infrared optical system accurately determines OD levels to monitor cell growth kinetics
  • Utilises 50 mL Falcon tubes with membrane filters to provide a working media volume of 10 mL - 30 mL
  • Temperature control range from 5°C above ambient to +70°C
  • Active cooling for rapid temperature control
  • Real-time cell growth logging
  • Software included for storage, demonstration and analysis of data in real-time
  • Up to 10 RTS-1 units can be simultaneously controlled by a PC through the software

Description

The RTS-1 is a single position bioreactor that utilises patented Reverse-Spin® technology to non-invasively optimise mixing and oxygenation for aerobic cell cultivation. With this novel technology a cell suspension in a single use 50 mL Falcon tube with a membrane filter is rotated around its axis in alternating directions to achieve a mass transfer coefficient (kLa (h-1)) of up to 450. This level of mass transfer is ideal for efficient aerobic cell culture.

The RTS-1 features a near-infrared optical system that uses a NIR light diode emitting at 850 nm. Highly accurate measurements of OD can be taken from 1 - 60 times per hour to provide a profile of cell growth in real-time. The temperature control range for the RTS-1 is 5°C above ambient to +70°C.

Key applications for the RTS-1 include:

  • Fermentation real time growth kinetics
  • Clone candidate screening
  • Protein expression
  • Temperature stress and fluctuation experiments
  • Media screening and optimisation
  • Growth characterisation
  • Inhibition and toxicity tests
  • Strain quality control

Specifications

Measurement range
0 - 10 OD at 10 - 20 mL volume (0 - 19 OD λ600 nm equivalent)
0 - 8 OD at 20 - 30 mL volume (0 - 15.2 OD λ600 nm equivalent)
Measurement precision
±0.3 OD
Light source
NIR light diode
Measurement wavelength (λ)
850 nm
Measurement periodicity per hour
1 - 60
Culture medium volume
10 mL - 30 mL
Temperature setting range
+25°C to +70°C
Temperature control range
5°C above ambient to +70°C
Temperature stability
±0.1°C
Display
LCD
Speed control range
50 rpm - 2000 rpm
Instrument dimensions (W x D x H)
130 mm x 212 mm x 200 mm
Weight
1.7 Kg
Power supply
Input: 100 - 240 VAC: 50/60 Hz
Output: 12 VDC: 3.3 A: 40 W


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About Us

Advance Scientific Products Pty Ltd is based in Queensland and is focused on delivering high-quality products and service to our customers in the life, chemical and analytical sciences across Australia.

The company was established in 2013 by experienced instrumentation specialists to provide full distribution and customer support capability to manufacturers seeking to expand their activities in Australia without having to create their own sales and marketing infrastructure.

Contact

PO Box 746
Moffat Beach, QLD, 4551, Australia